Differential effects of citalopram on sleep-deprivation-induced depressive-like behavior and memory impairments in mice

A Misrani, S Tabassum, X Chen, S Tan, J Wang… - Progress in Neuro …, 2019 - Elsevier
spatial memory deficits in mice, while subchronic administration of CTM to the S-Dep mice
ameliorates learning and memory deficits (… to S-Dep mice prevented synaptic plasticity deficits. …

Selective serotonin reuptake inhibitors and Alzheimer's disease

B Mdawar, E Ghossoub, R Khoury - Neural regeneration research, 2020 - journals.lww.com
… amyloid and tau deposits in mice, as well as … citalopram in drinking water for 4 months was
also shown to significantly decrease cortical and hippocampal plaque load on autopsy brain

[HTML][HTML] Spatial memory and gut microbiota alterations are already present in early adulthood in a pre-clinical transgenic model of Alzheimer's disease

PC Bello-Medina, F Hernández-Quiroz… - Frontiers in …, 2021 - frontiersin.org
mice (NoTg)], at 3 and 5 months old. We found spatial memory deficits in female and male
3xTg-AD but no … and synaptic plasticity alterations that could interfere with NOL consolidation …

[HTML][HTML] Spatial training ameliorates long-term alzheimer's disease-like pathological deficits by reducing NLRP3 inflammasomes in PR5 mice

QG Ren, WG Gong, H Zhou, H Shu, YJ Wang… - …, 2019 - Elsevier
… and improve memory performance in 3xTg-AD mice [4]. … decreased synaptic plasticity in the
10-month-old PR5 mice. … slices and improved spatial memory in AD transgenic mice [10, 24]. …

[HTML][HTML] Long-term exposure to polypharmacy impairs cognitive functions in young adult female mice

E Francesca, J Kristina, LL María, H Sarah… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… The impairments in explorative behavior and spatial memory … in regulating synaptic
plasticity and memory formation. We … by citalopram on fear associated memory in female mice

Dissecting the relationship between neuropsychiatric and neurodegenerative disorders

R Gupta, D Advani, D Yadav, RK Ambasta… - Molecular …, 2023 - Springer
… cognitive defects and memory impairment, whereas NPDs include depression, seizures,
migraine headaches, eating disorders, addictions, palsies, major depressive disorders, anxiety, …

Depression—an underrecognized target for prevention of dementia in Alzheimer's disease

FS Dafsari, F Jessen - Translational Psychiatry, 2020 - nature.com
… mechanisms in the impairment of neural plasticity in the … The chronic treatment with
Citalopram arrested the growth of … ameliorates forskolin-induced tau hyperphosphorylation and …

[HTML][HTML] Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice

F Eroli, K Johnell, ML Leal, C Adamo, S Hilmer… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
synaptic plasticity and important mediators of many forms of … citalopram and low-dose aspirin
improves deficits in memory … by metoprolol impaired contextual and spatial memory in rats …

Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-amyloid aggregation in a preclinical Alzheimer's disease model

PC Bello-Medina, K Corona-Cervantes… - International Journal of …, 2022 - mdpi.com
… On PD150, we observed a delay in spatial memory impairment … A model for studying AD is
the triple transgenic mouse (3xTg-AD), … Surprisingly, we found an amelioration in motor activity …

Citalopram and its use in sleep-deprivation-induced depression

A Misrani, C Long - The Neuroscience of Depression, 2021 - Elsevier
spatial memory and synaptic plasticity deficits and decrease the levels of insoluble Aβ 40 in
3xTgAD micememory by promoting synaptic plasticity and hippocampal neurogenesis in SD …